WALNUTS
Those who regularly consumed at least two, one-ounce servings of nuts each week demonstrated a 42% improvement in disease-free survival and a 57% improvement in overall survival.
- Evidence for risk reductions in multiple studies and cancers
- Lower all cause mortality risk frequently reported too
- Tree nuts in general contain these active compounds
COFFEE
This large cohort study detected an association between increased consumption of coffee and improved colorectal cancer outcomes.
- Coffee and its active ingredients can improve survival times
- Improved outcomes include for colorectal, gliomas and most breast cancers
- Population studies show preventative actions of coffee compounds
OATS
Non-significant reductions at 4 and 8 wk of 18 and 43%, respectively, were observed for serum amyloid A-1, an acute phase reactant in inflammation.
- Oat (and egg) based functional foods now entering clincial trials in several cancers
- Processed forms can reduce fluid pressure in tumors that drives growth, spread and resistance
- Avenanthramides entering phase IIa trials for inflammatory diseases, also high in processed oa...
SOY
Soy isoflavone intake was associated with significantly reduced risk of breast cancer recurrence for the overall population
- Tofu and soy milk show consistent benefit in many studies
- Population and clinical evidence is good, includes breast cancer
- Low in sulfur-containing amino acids cysteine and methionine
FLAX
These findings concur with the indications of links between eating soy 12 months or more after diagnosis and better breast cancer survival reported by WCRF/AICR
- Weight of evidence in breast cancer shows good relative risk reductions
- Small clinical trials show tendencies toward suppression for prostate cancer
- Some associated evidence in blood pressure and inflammation
BERRIES
These data provide evidence of the ability of BRBs [black raspberry] to demethylate tumor suppressor genes and to modulate other biomarkers of tumor developmentÂ
- Some clinical evidence from trials in colorectal cancer shows direct anti-cancer mechanisms
- Clear evidence that higher concentrations reduce vascular inflammation, platelet aggregation
- Evidence of metabolic benefits for insulin levels, LDL cholesterol also broad
MUSHROOMS
WBM appears to both impact PSA levels and modulate the biology of biochemically recurrent prostate cancer by decreasing immunosuppressive factors
- Emerging evidence in prostate cancer suppression
- Many positive clinical trials use mushroom extracts
- Boosting immune activity, reducing side effects in breast cancer
COCOA
serum concentrations of the soluble endothelium-derived adhesion molecules P-selectin and intercellular adhesion molecule-1 were significantly lower
- Evidence includes significant reductions in systemic oxidative stress
- Reduces platelet adhesion biomarkers that drive metastasis
- Positive and likely protective actions via microbiome, gut health
GARLIC
we observed significant decreases in levels of VCAM-1 and ICAM-1 in both healthy and hypercholesterolemic groups, whilst selectin levels significantly increased
- Inhibits markers of vascular health that drive metastasis
- Evidence of immune system health includes during oncology
- Also has actions on microbiome health
GREEN TEA
increased consumption of green tea prior to clinical cancer onset is significantly associated with improved prognosis of stage I and II breast cancer
- Some studies find reduced progression in breast and prostate cancer
- Recent meta-analysis shows preventative effect for breast cancer
- Also for reducing pain and side effects of radiotherapy
NATTO
The combined supplementation showed an advantage in anti-coagulation activities from increased antithrombin concentration, and down-regulating COX-1 related vasoconstriction, and apart from aspirin
- Reduces clotting, platelet aggregation and adhesion
- Strong synergies with red yeast rice (or statin)
- Separate actions complementary to aspirin use
TOMATO
Intake of tomatoes and tomato-based products and plasma levels of lycopene, a carotenoid found predominantly in tomatoes, have been relatively consistently associated with a lower risk of a variety of cancer
- Clear evidence to moderately reduce platelet activation and aggregation
- More clinical evidence of direct effects in cancer for lycopene is needed
- Metabolic benefits shown in some, not all, research studies
GINGER
..ginger supplementation may reduce proliferation in the crypts of the normal-appearing colorectal epithelium and increase apoptosis
- Direct anti-cancer activity evidence is limited, some positive indication for colorectal cancer
- Significant anti-inflammatory effects on biomarkers frequently seen raised during progression
- With existing systemic inflammatory disease, ginger can lower glucose, insulin and ...
TUMERIC
curcumin could exert its anticancer effect alone or in combination with other cancer drugs and is thus a potential novel therapy for breast cancer.
- Most evidence of benefit in cancers comes from curcumin
- Good evidence for metabolic benefits including inflammation
- Valuable chelation actions – for instance copper
BEETROOT
beetroot-carrot juice used as an adjuvant to chlorambucil [chemo] resulted in a substantial reduction in leukocytes and lymphocytes
- Dietary nitrate significantly increases endothelial (blood vessel) health
- Dysfunctional endothelium strongly indicated to increase metastasis
- Some evidence in reducing systemic inflammation and improved microbiome
BROCCOLI SPROUTS
glucoraphanin-rich broccoli soup affected gene expression in the prostate of men on active surveillance, consistent with a reduction in the risk of cancer progression
- Contributes to an anti-inflammation diet with sulforaphane
- Tendencies shown to slowing prostate cancer development
- Benefits metabolic health, LDL in particular
SEAWEEDS
..fucoidan-based approaches may provide important advances in overcoming the most complicated cancer drawbacks including metastasis
- Seaweed like wakame and kombu have many active health giving compounds, including fucodian
- In cancer there are evidence that these compounds can be beneficial in quality of life
- Effects on microbiome may indirectly improve important aspects of metabolic health
BLACK CUMIN SEED
potential to improve different clinical outcomes, such as blood glucose, inflammatory markers, oxidative stress factors, serum lipids
- Nigella Sativa class cumin seeds and oil also sold as supplements
- Some evidence of metabolic health benefits
- Mild anti-inflammatory actions
LONG PEPPER
The multi-targeted and pleiotropic nature of PL [piperlongumine] suggested that it might also be able to regulate complex phenomena such as chemoresistance
- Evidence in improved immune health , anti-inflammatory actions
- It has a long list of lab studies with many cancer cell types,
- Some clinical trials in cancer but no evidence of signficant effects